NMDA receptor antagonist

26 substances share this mechanism of action.

NMDA receptor antagonist (General (no qualifier))4 NMDA receptor antagonist (Ki = 66 nM)1 NMDA receptor antagonist (Ki ≈39 nM)1 NMDA receptor antagonist (Ki 20 nM)1 NMDA receptor antagonist (noncompetitive)14 NMDA receptor antagonist (rhynchophylline)1 NMDA receptor antagonist (selective ligand without appreciable dopamine transporter affinity)1 NMDA receptor antagonist (uncompetitive)2 NMDA receptor antagonist (uncompetitive, voltage-dependent)1

NMDA receptor antagonist (general)

4 substances

Psychedelic(1)

Tryptamine(1)

Ibogaine

Dissociative(1)

Diarylethylamine (substituted)(1)

Diphenidine

Opioid(2)

Common(2)

NMDA receptor antagonist (Ki = 66 nM)

1 substance

Dissociative(1)

Diarylethylamine (substituted)(1)

Ephenidine

NMDA receptor antagonist (Ki ≈39 nM)

1 substance

Dissociative(1)

Arylcyclohexylamine(1)

3-Me-PCPy

NMDA receptor antagonist (Ki 20 nM)

1 substance

Dissociative(1)

Arylcyclohexylamine(1)

3-MeO-PCP

NMDA receptor antagonist (noncompetitive)

14 substances

Dissociative(13)

Common(1)

Arylcyclohexylamine(11)

Diarylethylamine (substituted)(1)

2-Chloroephenidine

Miscellaneous(1)

3F-PCP

NMDA receptor antagonist (rhynchophylline)

1 substance

Opioid(1)

Common(1)

Kratom

NMDA receptor antagonist (selective ligand without appreciable dopamine transporter affinity)

1 substance

Dissociative(1)

Arylcyclohexylamine(1)

4-MeO-PCP

NMDA receptor antagonist (uncompetitive)

2 substances

Dissociative(2)

Common(2)

NMDA receptor antagonist (uncompetitive, voltage-dependent)

1 substance

Dissociative(1)

Other dissociatives(1)

Memantine

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