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mCPP

This article is a stubmissing:
Subjective Effects
Pharmacology
Tolerance
History & Culture
mCPP molecule structuremCPP molecule structure
1-(3-Chlorophenyl)piperazine
meta-Chlorophenylpiperazine, m-CPP
Psychoactive Class
Chemical Class

Dosage & Duration

Dosage

Doses are population estimates that vary widely between individuals.

Threshold15 mg
Light20-50 mg
Moderate50-120 mg
Strong120-150 mg
Heavy150+ mg

Duration

Onset20-60 minutes
Come Up20-60 minutes
Peak2-4 hours
Offset3-8 hours

Subjective Effects

Subjective Effects not written up yet

Reagent Testing

Expected colorimetric results for common reagent tests. Colors show reaction change over 1–2 minutes.

Marquis(MQ)
No reaction
No reaction
Mecke(ME)
No reaction
No reaction
Mandelin(MD)
No reaction
No reaction
Robadope(RB)
No reaction
No reaction
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Pharmacology

Pharmacology not written up yet

Interactions

Dangerous

Highest risk

These combinations are considered extremely harmful and should always be avoided. Reactions to these drugs taken in combination are highly unpredictable and have a potential to cause death.

5-HTPAlcoholCocaineDXMDissociativesMAOIsMDMAMXENBOMe compoundsSNRIsSSRIsSerotonin releasersStimulantsTramadol
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Tolerance

Tolerance not written up yet

Harm Potential

Addiction & Dependence

Psychological

Extremely Low

mCPP is not known to be addictive, though its addiction potential has not been formally studied. At common and high doses, it is generally regarded as aversive and dysphoria-producing, which likely limits compulsive redosing behavior.

Toxicity

Cardiovascular

Cardiovascular strain may occur during use, particularly at higher doses or when combined with other stimulants; the forced stimulation profile can increase heart rate and blood pressure.

Central Nervous System

mCPP is notable for inducing anxiety, migraines, and severe headaches, likely mediated through 5-HT2C receptor activity; these effects appear to be intrinsic to the substance rather than limited to excessive doses.

History & Culture

History & Culture not written up yet

Legality

By Country

Illegal12
Austria flagAustriaIllegal (analog/blanket ban)
Belgium flagBelgiumIllegal (analog/blanket ban)
Brazil flagBrazilIllegal
China flagChinaIllegal
Denmark flagDenmarkIllegal
Germany flagGermanyIllegal
Greece flagGreeceIllegal
Hungary flagHungaryIllegal
Japan flagJapanIllegal
Lithuania flagLithuaniaIllegal
Switzerland flagSwitzerlandIllegal
United Kingdom flagUnited KingdomIllegal
Controlled / restricted5
Finland flagFinlandmCPP is a controlled substance.
Norway flagNorwaymCPP is a controlled substance.
Poland flagPolandmCPP is a controlled substance.
Russia flagRussiamCPP is a controlled substance.
Sweden flagSwedenmCPP is a controlled substance.
Not scheduled1
United States flagUnited StatesNot scheduled

References

Source Pages

  1. Erowid
  2. Erowid: mCPP Experience Vault
  3. Isomer Design (TiHKAL/PiHKAL)
  4. PsychonautWiki
  5. TripSit Factsheets
  6. Wikipedia
  7. Wikipedia: meta-Chlorophenylpiperazine

Citations

  1. 我国管制毒品目录(2026年7月更新,540种+三大类). ga.sz.gov.cn (n.d.). https://ga.sz.gov.cn/SZJDZX/SZBMFW/content/post_12898420.html1
  2. 三部门联合发布最新版《非药用类麻醉药品和精神药品目录》. btgaj.xjbt.gov.cn (n.d.). https://btgaj.xjbt.gov.cn/c/2025-07-28/8428464.shtml1
  3. 非药用类麻醉药品和精神药品列管办法. gaj.panjin.gov.cn (n.d.). https://gaj.panjin.gov.cn/2015_10/08_00/content-235605.html1
  4. e-Gov current text: 麻薬、麻薬原料植物、向精神薬、麻薬向精神薬原料等を指定する政令(平成二年政令第二百三十八号). laws.e-gov.go.jp (n.d.). https://laws.e-gov.go.jp/api/1/lawdata/402CO00000002381
  5. 厚生労働省通知:麻薬及び向精神薬取締法施行令等の一部を改正する政令及び麻薬及び向精神薬取締法施行規則の一部を改正する省令の施行について(平成18年9月13日薬食発第0913001号). mhlw.go.jp (n.d.). https://www.mhlw.go.jp/web/t_doc?dataId=00tb3870&dataType=1&pageNo=11
  6. e-Gov current text: 麻薬及び向精神薬取締法(昭和二十八年法律第十四号). laws.e-gov.go.jp (n.d.). https://laws.e-gov.go.jp/api/1/lawdata/328AC00000000141
  7. Portaria - PRT nº 344, de 12/05/1998 — Anexo I, Lista F2. anvisalegis.datalegis.net (n.d.). https://anvisalegis.datalegis.net/action/ActionDatalegis.php?acao=abrirTextoAto&tipo=POR&numeroAto=00000344&seqAto=000&valorAno=1998&orgao=SVS%2FMS&codTipo=&desItem=&desItemFim=&cod_menu=1696&cod_modulo=134&pesquisa=true1
  8. Lista de substâncias sujeitas a controle especial no Brasil. gov.br (n.d.). https://www.gov.br/anvisa/pt-br/assuntos/medicamentos/controlados/lista-substancias1
  9. Resolução da Diretoria Colegiada - RDC nº 79, de 04/11/2008. anvisalegis.datalegis.net (n.d.). https://anvisalegis.datalegis.net/action/ActionDatalegis.php?acao=detalharAto&cod_menu=1696&cod_modulo=134&nomeTitulo=codigos&numeroAto=00000079&orgao=RDC%2FDC%2FANVISA%2FMS&seqAto=000&tipo=RDC&valorAno=20081
  10. Voto nº 110/2020/SEI/DIRE1/Anvisa. gov.br (n.d.). https://www.gov.br/anvisa/pt-br/composicao/diretoria-colegiada/reunioes-da-diretoria/votos/2020/rop-22.2020/item-3-1-3-5-voto-110-2020-dire1.pdf/@@display-file/file1

Further Reading

  1. Bossong et al. 2010: mCPP Ecstasy Market Study
  2. Gijsman et al. 2002: Pharmacokinetic Profile of mCPP
  3. Kennett et al. 1989: Anxiogenic Effects of mCPP
  4. Leone et al. 2000: mCPP-Induced Migraine Study
  5. NCATS Inxight Drugs: mCPP Monograph
  6. PDSP Ki Database: mCPP Receptor Binding
  7. Release UK: mCPP Pharmacology
  8. Rotzinger et al. 1998: CYP2D6 Metabolism of mCPP

Article Status

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    An autonomous workflow built by Josie Kins compiled this article's foundation from information published across the web.

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