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4-MPM

This article is a stubmissing:
Subjective Effects
Interactions
Legality
4-MPM molecule structure4-MPM molecule structure
4-Methylphenmetrazine
mephenmetrazine, PAL-747Open in Piru
Psychoactive Class
StimulantEntactogen
Chemical Class
Phenylmorpholine (substituted)

4-Methylphenmetrazine (4-MPM) is a substituted phenylmorpholine with stimulant and empathogenic effects. It is a phenmetrazine analog encountered on the new psychoactive substance market following the introduction of 3-fluorophenmetrazine1. Reports indicate that tolerance develops rapidly, and classification sources describe 4-MPM as potentially habit-forming. It was first identified in Slovenia in 2015.

Dosage & Duration

Log in Piru

Dosage

Doses are population estimates that vary widely between individuals.

Threshold~5 mg
Light5-10 mg
Moderate10-20 mg
Strong20-25 mg
Heavy25+ mg

Subjective Effects

Subjective Effects not written up yet

Reagent Testing

Expected colorimetric results for common reagent tests. Colors show reaction change over 1–2 minutes.

Marquis(MQ)
white → green2 → blue2
Mandelin(MD)
yellow2 → green2 → brown2
Froe(FR)
white → purple2
Simons(SI)
orange1 → blue2
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Pharmacology

Pharmacodynamics

In in vitro rat brain synaptosome assays, 4-MPM was characterized as an essentially nonselective monoamine releaser1.

Pharmacokinetics

Absorption & half-lifenot documented yetMetabolitesnone documented yet

Interactions

Interactions not written up yet

An unlisted combination is an unknown one, not a safe one. Check a dedicated combination chart before mixing.

Check TripSit

Tolerance

Tolerance timelines are rules of thumb, not exact schedules, and vary widely between individuals and use patterns.

Full Tolerance
Reports indicate that tolerance to 4-MPM develops rapidly with use.

Harm Potential

Addiction & Dependence

Psychological

Moderate

Classified as habit-forming with reports indicating tolerance builds quickly, suggesting potential for compulsive use patterns typical of stimulant-entactogen compounds.

History & Culture

4-MPM was first identified in Slovenia in 2015. It was identified as a phenmetrazine analog encountered on the new psychoactive substance market following the introduction of 3-fluorophenmetrazine1.

Legality

Legality not written up yet

References

Source Pages

  1. Bluelight thread: Novel stimulant 4-MPM
  2. Bluelight: user report (insufflated ≈100 mg)
  3. PiHKAL.info: 4-MPM chemical data
  4. Wikipedia
  5. Wikipedia: Monoamine releasing agent table

Citations

  1. Synthesis, analytical characterization and monoamine transporter activity of the new psychoactive substance 4-methylphenmetrazine (4-MPM), with differentiation from its ortho- and meta-positional isomers. Drug Testing and Analysis (2018). https://doi.org/10.1002/dta.2396123

Further Reading

  1. Drugs-Forum: 4-MPM experience report (highganja99)
  2. McLaughlin et al. 2018 PMC Full Text
  3. PubChem: 4-Methylphenmetrazine
  4. Reddit r/researchchemicals: 4-MPM compared to 3-FPM
  5. Reddit r/researchchemicals: 4-MPM first impression
  6. ResearchChemsLab vendor spec
  7. TeamChemists product page

Article Status

  • Josie Kins avatar
    Step 1 · Automated synthesis

    An autonomous workflow built by Josie Kins compiled this article's foundation from information published across the web.

  • Step 2 · First-pass reviewPending

    Not yet reviewed: this article is pending editorial review by Lyrea.

  • Step 3 · Citation reviewPending

    No one has reviewed this article's citations yet. That second pass checks each claim against the source it cites.

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