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NEB

This article is a stubmissing:
Subjective Effects
Interactions
Tolerance
Legality
NEB molecule structureNEB molecule structure
Open in Piru
Chemical Class
Cathinone

NEB is a stimulant in the synthetic cathinone class1 that has been sold as a designer drug. It was first reported around 2011. Its effects are short-lived, and anecdotal reports suggest some similarities to those of other cathinones. It is classified as habit-forming.

Dosage & Duration

Log in Piru

Dosage

Doses are population estimates that vary widely between individuals.

Threshold~10 mg
Light10-15 mg
Moderate15-30 mg
Strong30-45 mg
Heavy45+ mg

Subjective Effects

Subjective Effects not written up yet

Reagent Testing

Expected colorimetric results for common reagent tests. Colors show reaction change over 1–2 minutes.

Marquis(MQ)
white → yellow1 → orange1
Morr(MO)
pink2 → green1
Zimm(ZI)
white → white1 → yellow1
Mecke(ME)
No reaction
No reaction
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Pharmacology

Pharmacodynamics

NEB has greater potency at inhibiting dopamine uptake than serotonin uptake in transfected HEK293 cells expressing human transporters.2

Pharmacokinetics

Absorption & half-lifenot documented yetMetabolitesnone documented yet

Interactions

Interactions not written up yet

An unlisted combination is an unknown one, not a safe one. Check a dedicated combination chart before mixing.

Check TripSit

Tolerance

Tolerance not written up yet

Harm Potential

Addiction & Dependence

Psychological

Moderate

NEB is considered a habit-forming stimulant research chemical.

History & Culture

N-Ethylbuphedrone (NEB) was first reported around 2011 and was sold as a designer drug. It reportedly did not achieve widespread popularity.

Legality

Legality not written up yet

References

Citations

  1. Substance Details N-Ethylbuphedrone. United Nations Office on Drugs and Crime (n.d.). https://www.unodc.org/LSS/Substance/Details/ff4b0258-3e63-42dd-b15e-bed8d4780c321
  2. Structure-activity relationship of /N-ethyl-hexedrone analogues: Role of the α-carbon side-chain length in the mechanism of action, cytotoxicity, and behavioral effects in mice. ACS Chemical Neuroscience (2023). https://doi.org/10.1021/acschemneuro.2c007721

Article Status

  • Josie Kins avatar
    Step 1 · Automated synthesis

    An autonomous workflow built by Josie Kins compiled this article's foundation from information published across the web.

  • Step 2 · First-pass reviewPending

    Not yet reviewed: this article is pending editorial review by Lyrea.

  • Step 3 · Citation reviewPending

    No one has reviewed this article's citations yet. That second pass checks each claim against the source it cites.

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