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Metaclazepam

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Subjective Effects
Interactions
Tolerance
History & Culture
Legality
Metaclazepam molecule structureMetaclazepam molecule structure
Open in Piru
Chemical Class
1,4-Benzodiazepine

Metaclazepam is a benzodiazepine with anxiety-reducing effects reported in a two-week study of patients with an anxiety disorder1 and comparatively limited sedative and muscle-relaxing properties. It is described as slightly more effective at reducing anxiety than bromazepam or diazepam. It can be habit-forming, and fatigue is a common side effect at high doses. Combining metaclazepam with alcohol can produce additive sedation and sleep-inducing effects.

Dosage & Duration

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Dosage

Doses are population estimates that vary widely between individuals.

Moderate18.75 mg
Strong35-50 mg
Heavy50+ mg

Duration

After Effects1-24 hours

Subjective Effects

Subjective Effects not written up yet

Pharmacology

Pharmacokinetics

Metaclazepam is metabolized primarily to an active metabolite. Metabolism does not differ significantly between younger and older individuals. Small amounts of the drug and its metabolites pass into human breast milk.2

Interactions

Interactions not written up yet

An unlisted combination is an unknown one, not a safe one. Check a dedicated combination chart before mixing.

Check TripSit

Tolerance

Tolerance not written up yet

Harm Potential

Addiction & Dependence

Psychological

Moderate

Classified as habit-forming, consistent with the psychological dependence potential typical of benzodiazepine-class compounds.

History & Culture

History & Culture not written up yet

Legality

Legality not written up yet

References

Citations

  1. Controlled study on the anxiolytic activity of a newly-developed benzodiazepine, metaclazepam. Current Medical Research and Opinion / PubMed (1988). https://doi.org/10.1185/030079988091111291
  2. Transfer of metaclazepam and its metabolites into breast milk.. GreenMedInfo, reproducing the Arzneimittelforschung research abstract (1989). https://uat.greenmedinfo.com/abstracts/transfer-of-metaclazepam-and-its-metabolites-into-breast-milk-25759071

Article Status

  • Josie Kins avatar
    Step 1 · Automated synthesis

    An autonomous workflow built by Josie Kins compiled this article's foundation from information published across the web.

  • Step 2 · First-pass reviewPending

    Not yet reviewed: this article is pending editorial review by Lyrea.

  • Step 3 · Citation reviewPending

    No one has reviewed this article's citations yet. That second pass checks each claim against the source it cites.

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