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Meclofenoxate

This article is a stubmissing:
Subjective Effects
Pharmacology
Interactions
Tolerance
History & Culture
Meclofenoxate molecule structureMeclofenoxate molecule structure
2-Dimethylaminoethyl (4-chlorophenoxy)acetate
Centrophenoxine, Lucidril, Helfergin, ANP 235
Psychoactive Class
Nootropic
Chemical Class
Choline derivative

Dosage & Duration

Dosage

Doses are population estimates that vary widely between individuals.

Threshold50 mg
Light50-200 mg
Moderate400-800 mg
Strong800-1000 mg
Heavy600+ mg

Duration

Total4-8 hours

Subjective Effects

Subjective Effects not written up yet

Pharmacology

Pharmacology not written up yet

Interactions

Interactions not written up yet

An unlisted combination is an unknown one, not a safe one. Check a dedicated combination chart before mixing.

Check TripSit

Tolerance

Tolerance not written up yet

Harm Potential

Addiction & Dependence

Psychological

Extremely Low

Meclofenoxate is considered non-addictive with no documented abuse potential or reinforcing properties.

Physical

Extremely Low

No physical dependence or withdrawal symptoms have been reported.

Seizure Risk

Meclofenoxate is contraindicated in individuals with epilepsy or a history of convulsions, suggesting potential seizure threshold effects, though specific risk data is not characterized.

History & Culture

History & Culture not written up yet

Legality

By Country

Not scheduled1
United States flagUnited StatesNot scheduled

References

Source Pages

  1. Erowid
  2. Erowid: Meclofenoxate Vault
  3. Isomer Design (TiHKAL/PiHKAL)
  4. Meclofenoxate DrugBank Entry
  5. PsychonautWiki
  6. TripSit Factsheets
  7. Wikipedia

Citations

  1. MECLOFENOXATE HYDROCHLORIDE — UNII 5BK3070BDY. precision.fda.gov (n.d.). https://precision.fda.gov/uniisearch/srs/unii/5BK3070BDY1
  2. 21 C.F.R. Part 1308—Schedules of Controlled Substances (2025 annual edition). govinfo.gov (n.d.). https://www.govinfo.gov/content/pkg/CFR-2025-title21-vol9/xml/CFR-2025-title21-vol9-part1308.xml1
  3. Controlled Substances—Alphabetical Order. deadiversion.usdoj.gov (n.d.). https://www.deadiversion.usdoj.gov/schedules/orangebook/c_cs_alpha.pdf1
  4. Scheduling Actions—Alphabetical Order. deadiversion.usdoj.gov (n.d.). https://www.deadiversion.usdoj.gov/schedules/orangebook/a_sched_alpha.pdf1
  5. List I and II Regulated Chemicals—Alphabetical Order. deadiversion.usdoj.gov (n.d.). https://www.deadiversion.usdoj.gov/schedules/orangebook/f_chemlist_alpha.pdf1
  6. DEA Diversion Control Division — Controlled Substance Schedules. deadiversion.usdoj.gov (n.d.). https://www.deadiversion.usdoj.gov/schedules/schedules.html1
  7. Federal Register API — Drug Enforcement Administration documents since 28 August 2026. federalregister.gov (n.d.). https://www.federalregister.gov/api/v1/documents.json?conditions%5Bagencies%5D%5B%5D=drug-enforcement-administration&conditions%5Bpublication_date%5D%5Bgte%5D=08%2F28%2F2026&per_page=100&order=newest1
  8. 21 U.S.C. § 321 — Definitions; generally. uscode.house.gov (n.d.). https://uscode.house.gov/view.xhtml?req=granuleid:USC-prelim-title21-section321&num=0&edition=prelim1
  9. Submitted 75-Day Premarket Notifications for New Dietary Ingredients. fda.gov (n.d.). https://www.fda.gov/food/new-dietary-ingredient-ndi-notification-process/submitted-75-day-premarket-notifications-new-dietary-ingredients1
  10. FDA New Dietary Ingredient Notification List, 1995 to Present (9 July 2026). fda.gov (n.d.). https://www.fda.gov/media/193535/download?attachment1

Further Reading

  1. Alzheimer's Drug Discovery Foundation: Centrophenoxine Review
  2. Hochschild 1973: Effect on lifespan in mice
  3. Malík & Tlustoš 2022: Nootropics as Cognitive Enhancers
  4. Nootropics Expert: Centrophenoxine
  5. SelfHacked: Centrophenoxine Guide
  6. Stancheva & Alova: MAO inhibition study
  7. USADA: Meclofenoxate Information
  8. Vinmec: Uses of Lucimax

Article Status

  • Josie Kins avatar
    Step 1 · Automated synthesis

    An autonomous workflow built by Josie Kins compiled this article's foundation from information published across the web.

  • Step 2 · First-pass reviewPending

    Not yet reviewed: this article is pending editorial review by Lyrea.

  • Step 3 · Citation reviewPending

    No one has reviewed this article's citations yet. That second pass checks each claim against the source it cites.

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