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Lagochilus-Inebrians

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Subjective Effects
Interactions
Tolerance
Legality
Lagochilus-Inebrians molecule structureLagochilus-Inebrians molecule structure

Lagochilus inebrians is a shrub1 in the mint family1, native to Uzbekistan, Turkmenistan, and Tajikistan.2 It may produce mild euphoria and sedation.3 The plant was traditionally prepared as a tea in Turkestan, where Tajik, Tatar, Turkmen, and Uzbek communities used it.4 Its pronounced bitterness often leads to the addition of sugar or honey to the tea.

Dosage & Duration

Log in Piru

Dosage

Doses are population estimates that vary widely between individuals.

Moderate2-10 mg

Duration

Onset10-30 minutes
Total3-5 hours

Subjective Effects

Subjective Effects not written up yet

Pharmacology

Pharmacodynamics

Stachydrine, a constituent of Lagochilus inebrians,5 dose-dependently inhibited tissue factor expression in human umbilical vein endothelial cells subjected to oxygen deprivation followed by reoxygenation. In this cell model, it also reduced reactive oxygen species production and inflammation and improved cell survival.

Pharmacokinetics

Absorption & half-lifenot documented yetMetabolitesnone documented yet

Interactions

Interactions not written up yet

An unlisted combination is an unknown one, not a safe one. Check a dedicated combination chart before mixing.

Check TripSit

Tolerance

Tolerance not written up yet

Harm Potential

Toxicity

Central nervous system and coordination

Negative effects include drowsiness, cognitive impairment, unsteady gait, and experience-based reports of impaired balance.

Gastrointestinal

Negative effects include nausea and vomiting.

History & Culture

Lagochilus inebrians was used as a tea in Turkestan for at least several centuries, although the beginning of this tradition was unknown. Its use was recorded among Tajik, Tatar, Turkmen, and Uzbek communities.4 Traditional preparation generally involved collecting the…

Legality

Legality not written up yet

Article Status

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    Step 1 · Automated synthesis

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