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HOT-2

This article is a stubmissing:
Subjective Effects
Pharmacology
Interactions
Tolerance
History & Culture
HOT-2 molecule structureHOT-2 molecule structure
Chemical Class
2C-X

Dosage & Duration

Dosage

Doses are population estimates that vary widely between individuals.

Threshold8 mg
Light10-12 mg
Moderate10-18 mg
Strong15-18 mg
Heavy18+ mg

Duration

Onset20-40 minutes
After Effects1-12 hours
Total5-12 hours

Subjective Effects

Subjective Effects not written up yet

Pharmacology

Pharmacology not written up yet

Interactions

Interactions not written up yet

An unlisted combination is an unknown one, not a safe one. Check a dedicated combination chart before mixing.

Check TripSit

Tolerance

Tolerance not written up yet

Harm Potential

Toxicity

Cardiovascular

Acute cardiovascular effects including elevated blood pressure and increased heart rate occur during intoxication; blood pressure elevations were noted to return to normal relatively quickly in documented experiences.

Psychosis Risk

Mental confusion and difficulty concentrating have been reported during intoxication. Psychological discomfort and difficulty communicating were noted in some experiences.

History & Culture

History & Culture not written up yet

Legality

By Country

Illegal1
United States flagUnited StatesIllegal (analog/blanket ban)

References

Citations

  1. Solicitation of Information on the Use of Phenethylamine-Related Compounds, 71 Fed. Reg. 62017. govinfo.gov (n.d.). https://www.govinfo.gov/content/pkg/FR-2006-10-20/pdf/E6-17523.pdf1
  2. Lists of Scheduling Actions, Controlled Substances, Regulated Chemicals — August 2026. deadiversion.usdoj.gov (n.d.). https://www.deadiversion.usdoj.gov/schedules/orangebook/orangebook.pdf1
  3. DEA Diversion Control Division — Controlled Substance Schedules. deadiversion.usdoj.gov (n.d.). https://www.deadiversion.usdoj.gov/schedules/schedules.html1
  4. 21 U.S.C. § 802 — Definitions. uscode.house.gov (n.d.). https://uscode.house.gov/view.xhtml?req=granuleid:USC-prelim-title21-section802&num=0&edition=prelim1
  5. 21 U.S.C. § 813 — Treatment of controlled substance analogues. uscode.house.gov (n.d.). https://uscode.house.gov/view.xhtml?req=granuleid:USC-prelim-title21-section813&num=0&edition=prelim1
  6. 21 U.S.C. § 841 — Prohibited acts A. uscode.house.gov (n.d.). https://uscode.house.gov/view.xhtml?req=granuleid:USC-prelim-title21-section841&num=0&edition=prelim1
  7. 21 U.S.C. § 844 — Penalties for simple possession. uscode.house.gov (n.d.). https://uscode.house.gov/view.xhtml?req=granuleid:USC-prelim-title21-section844&num=0&edition=prelim1

Article Status

  • Josie Kins avatar
    Step 1 · Automated synthesis

    An autonomous workflow built by Josie Kins compiled this article's foundation from information published across the web.

  • Step 2 · First-pass reviewPending

    Not yet reviewed: this article is pending editorial review by Lyrea.

  • Step 3 · Citation reviewPending

    No one has reviewed this article's citations yet. That second pass checks each claim against the source it cites.

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