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Flutazolam

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Subjective Effects
Interactions
Tolerance
Legality
Flutazolam molecule structureFlutazolam molecule structure
Open in Piru
Chemical Class
Benzodiazepine

Flutazolam is a benzodiazepine1 depressant2 with sedative and hypnotic effects.1 It was developed in Japan, where it is primarily used medically to treat insomnia. Its potency is similar to diazepam, but it produces more pronounced sedation and impaired coordination. Flutazolam is habit-forming3 and may cause amnesia and reduced inhibitions at high doses.

Dosage & Duration

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Dosage

Doses are population estimates that vary widely between individuals.

Threshold~2.5 mg
Light2.5-5 mg
Moderate5-10 mg
Strong10-15 mg
Heavy15+ mg

Duration

Onset10-30 minutes
After Effects1-12 hours
Total3-8 hours

Subjective Effects

Subjective Effects not written up yet

Pharmacology

Pharmacokinetics

Flutazolam has a half-life of 3.5 hours.4 Its major active metabolite has a considerably longer half-life of 47-100 hours.

Interactions

Interactions not written up yet

An unlisted combination is an unknown one, not a safe one. Check a dedicated combination chart before mixing.

Check TripSit

Tolerance

Tolerance not written up yet

Harm Potential

Addiction & Dependence

Psychological

Moderate

Classified as habit-forming, consistent with the benzodiazepine class which carries moderate psychological addiction potential with regular use.

History & Culture

Flutazolam was developed in Japan, which was also the principal country in which it was used medically.

Legality

Legality not written up yet

References

Citations

  1. KEGG DRUG: Flutazolam. KEGG (n.d.). https://www.kegg.jp/entry/D0128612
  2. コレミナール錠4mg/細粒1% — prescribing information. Pharmaceuticals and Medical Devices Agency (2023). https://www.pmda.go.jp/PmdaSearch/iyakuDetail/ResultDataSetPDF/300119_1124024C1035_1_101
  3. Revision of Precautions: Flutazolam. Ministry of Health, Labour and Welfare / Pharmaceuticals and Medical Devices Agency (2017). https://www.pmda.go.jp/files/000219597.pdf1
  4. コレミナール錠4mg/細粒1% prescribing information. Sawai Pharmaceutical (2019). https://www.koizumi-generic-drug-information-research-2nd-ver.com/wp-content/uploads/2019/10/300119_1124024C1035_1_09.pdf1

Article Status

  • Josie Kins avatar
    Step 1 · Automated synthesis

    An autonomous workflow built by Josie Kins compiled this article's foundation from information published across the web.

  • Step 2 · First-pass reviewPending

    Not yet reviewed: this article is pending editorial review by Lyrea.

  • Step 3 · Citation reviewPending

    No one has reviewed this article's citations yet. That second pass checks each claim against the source it cites.

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