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Coluracetam

This article is a stubmissing:
Subjective Effects
Pharmacology
Tolerance
History & Culture
Coluracetam molecule structureColuracetam molecule structure
BCI-540, MKC-231
Psychoactive Class
NootropicStimulant (mild)
Chemical Class
Racetam

Dosage & Duration

Dosage

Doses are population estimates that vary widely between individuals.

Threshold1 mg
Light2-5 mg
Moderate5-10 mg
Strong10+ mg
Heavy20+ mg

Duration

Onset1-5 minutes
Total3-6 hours

Subjective Effects

Subjective Effects not written up yet

Reagent Testing

Expected colorimetric results for common reagent tests. Colors show reaction change over 1–2 minutes.

Marquis(MQ)
No reaction
No reaction
Mecke(ME)
No reaction
No reaction
Mandelin(MD)
No reaction
No reaction
Liebermann(LB)
No reaction
No reaction
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Pharmacology

Pharmacology not written up yet

Interactions

Dangerous

Highest risk

These combinations are considered extremely harmful and should always be avoided. Reactions to these drugs taken in combination are highly unpredictable and have a potential to cause death.

DissociativesStimulants
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Tolerance

Tolerance not written up yet

Harm Potential

Addiction & Dependence

Psychological

Extremely Low

Chronic coluracetam use is generally described as non-addictive and low in abuse potential, with no clear indication that it produces psychological dependence in users.

History & Culture

History & Culture not written up yet

Legality

By Country

Prescription1
Australia flagAustraliaPrescription only

References

Source Pages

  1. Bluelight: Coluracetam user thread (2013)
  2. Isomer Design (TiHKAL/PiHKAL)
  3. PsychonautWiki
  4. TripSit Factsheets
  5. Wikipedia

Citations

  1. Therapeutic Goods (Poisons Standard—June 2026) Instrument 2026 — Federal Register record. legislation.gov.au (n.d.). https://www.legislation.gov.au/F2026L00633/latest/text1
  2. Therapeutic Goods (Poisons Standard—June 2026) Instrument 2026. legislation.gov.au (n.d.). https://www.legislation.gov.au/F2026L00633/asmade/2026-05-28/text/original/epub/OEBPS/document_1/document_1.html1

Further Reading

  1. Bessho et al. (1996) - Effect on water maze learning deficits
  2. Braintropic - Coluracetam Overview
  3. Murai et al. (1994) - MKC-231 ameliorates working memory deficits
  4. NootropicsExpert - Coluracetam Review
  5. Reddit: r/Nootropics – How do you dose Coluracetam? (2014)
  6. Reddit: r/Nootropics – Long-term tolerance report (2015)
  7. SelfDecode – Coluracetam interactions
  8. Shirayama et al. (2007) - MKC-231 antagonizes phencyclidine-induced deficits
  9. Takashina et al. (2008) - MKC-231 mode of action in choline uptake

Article Status

  • Josie Kins avatar
    Step 1 · Automated synthesis

    An autonomous workflow built by Josie Kins compiled this article's foundation from information published across the web.

  • Step 2 · First-pass reviewPending

    Not yet reviewed: this article is pending editorial review by Lyrea.

  • Step 3 · Citation reviewPending

    No one has reviewed this article's citations yet. That second pass checks each claim against the source it cites.

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