white → brown1
WARNINGMIXING OR WITHDRAWAL CAN BE DANGEROUS
Ordinary doses in combination with other depressants can fatally stop breathing. After prolonged dependency, stopping suddenly can also cause seizures or delirium; seek medical help.
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Cloniprazepam
Cloniprazepam is a designer benzodiazepine for which nine metabolites were identified, with clonazepam as the major metabolite1. It is a designer benzodiazepine within the emerging class of new psychoactive substances2. TripSit also categorizes it as habit-forming, although its psychoactive classification remains unknown. In vitro studies identified nine metabolites of cloniprazepam, with clonazepam as the major metabolite1.
Dosage & Duration
Dosage
Doses are population estimates that vary widely between individuals.
Threshold~0.5 mg
Light0.5-1 mg
Moderate1-2 mg
Strong2-4 mg
Heavy4+ mg
Duration
Onset15-45 minutes
After Effects1-8 hours
Total6-9 hours
Subjective Effects
Legacy content. A statistically backed ontology from Mindstate Design Labs is coming soon.
Effects vary widely by individual, dose, and context.
Physical
The physical effects of cloniprazepam can be broken down into several components which progressively intensify proportional to dosage.
Cognitive
The cognitive effects of cloniprazepam can be broken down into several components which progressively intensify proportional to dosage. The general head space of cloniprazepam is described by many as one of intense relaxation, anxiety suppression and decreased inhibition. It contains a large number of typical depressant cognitive effects. Paradoxical reactions to benzodiazepines such as increased seizures (in epileptics), aggression, increased anxiety, violent behavior, loss of impulse control, irritability and suicidal behavior sometimes occur (although they are rare in the general population, with an incidence rate below 1%). These paradoxical effects occur with greater frequency in recreational abusers, individuals with mental disorders, children, and patients on high-dosage regimes.
Adapted from the Clonazepam subjective effects documentation. Cloniprazepam is a prodrug of clonazepam and is reported to produce an effectively identical experience. Forked from Subjective Effect Documentation by
Josie Kins September 2015.
Josie Kins September 2015.
Pharmacology
Pharmacokinetics
Cloniprazepam is a prodrug converted to clonazepam, 7-aminoclonazepam, and other metabolites.3 Minor metabolic products are also formed.
Interactions
Interactions not written up yet
An unlisted combination is an unknown one, not a safe one. Check a dedicated combination chart before mixing.
Tolerance
Tolerance not written up yet
Harm Potential
Addiction & Dependence
Psychological
Cloniprazepam has psychological addiction potential and is described as habit-forming.
Physical
Cloniprazepam has physical addiction potential; abrupt discontinuation can cause life-threatening withdrawal.
Seizure Risk
Abrupt discontinuation of cloniprazepam can cause life-threatening withdrawal with seizures.
History & Culture
History & Culture not written up yet
Legality
Legality not written up yet
References
Citations
Article Status
Step 1 · Automated synthesisAn autonomous workflow built by Josie Kins compiled this article's foundation from information published across the web.
- Step 2 · First-pass reviewPending
Not yet reviewed: this article is pending editorial review by Lyrea.
- Step 3 · Citation reviewPending
No one has reviewed this article's citations yet. That second pass checks each claim against the source it cites.
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