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Characterized by high potency relative to typical opioids; careful titration strongly recommended.
Classified as habit-forming. As a potent synthetic opioid and fentanyl analog, it carries significant abuse potential.
Potentially fatal in overdose due to respiratory depression. Active doses are in the microgram range, indicating high potency and a narrow margin between effective and dangerous doses. Fentanyl analogs have killed hundreds of people throughout Europe and the former Soviet republics since the early 2000s.
Butyrfentanyl first appears in scientific literature through documentation by the College on Problems of Drug Dependence, where it was referenced as an N-butyramide fentanyl analog. Pharmacological characterization of the compound—including analgesic efficacy studies, opioid receptor binding…
UN Single Convention on Narcotic Drugs 1961 (Schedule I, added March 2017)
Designated as a controlled substance since October 2015 under national narcotics legislation.
Controlled as a fentanyl analogue under provisions covering modifications of fentanyl through replacement of the N-propionyl group with another acyl group.
Prohibited since December 2015 under Swiss controlled substances regulations.
Classified as a Schedule I controlled substance under federal law since May 2016. Possession, distribution, and manufacture are prohibited with no accepted medical use.