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Allobarbital

This article is a stubmissing:
Subjective Effects
Pharmacology
Interactions
Tolerance
Legality
Allobarbital molecule structureAllobarbital molecule structure
Open in Piru
Chemical Class
Barbiturate

Allobarbital is a barbiturate derivative first synthesized in 1912 by Ernst Preiswerk and Ernst Grether at CIBA. It was combined in analgesic preparations1, although their enhanced efficacy was not firmly established1, and was used to induce sedation1 or treat insomnia2 and anxiety. Newer drugs with improved safety profiles have largely replaced it, although it remained in use in Poland and some other European countries.

Dosage & Duration

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Dosage

Doses are population estimates that vary widely between individuals.

Threshold~500 mg
Light500-1000 mg
Moderate1000-1500 mg
Strong1500-2000 mg
Heavy2000+ mg

Duration

Onset15-30 minutes
After Effects1-12 hours
Total6-10 hours

Subjective Effects

Subjective Effects not written up yet

Pharmacology

Pharmacology not written up yet

Interactions

Interactions not written up yet

An unlisted combination is an unknown one, not a safe one. Check a dedicated combination chart before mixing.

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Tolerance

Tolerance not written up yet

Harm Potential

Addiction & Dependence

Psychological

High

Barbiturates as a class are considered habit-forming with significant psychological addiction potential.

History & Culture

Allobarbital was invented in 1912 by Ernst Preiswerk and Ernst Grether while working for CIBA. It was used primarily as an anticonvulsant, and also as an adjunct to analgesic drugs and in the treatment of insomnia and anxiety, before newer medicines with improved safety profiles largely replaced it.…

Legality

Legality not written up yet

References

Citations

  1. Allobarbital. Expert Committee on Drug Dependence Information Repository (1987). https://ecddrepository.org/en/allobarbital123
  2. Barbiturates drug profile. European Union Drugs Agency (n.d.). https://www.euda.europa.eu/publications/drug-profiles/barbiturates_en1
  3. Psychotropic Substances: Statistics for 2011, Assessments of Annual Medical and Scientific Requirements. Colombia Ministry of Justice and Law, hosting an International Narcotics Control Board report (2012). https://www.minjusticia.gov.co/programas-co/ODC/Publicaciones/Publicaciones/IN1022012_psychotropic_substances_sustancias_sicotropicas_2012.pdf1

Article Status

  • Josie Kins avatar
    Step 1 · Automated synthesis

    An autonomous workflow built by Josie Kins compiled this article's foundation from information published across the web.

  • Step 2 · First-pass reviewPending

    Not yet reviewed: this article is pending editorial review by Lyrea.

  • Step 3 · Citation reviewPending

    No one has reviewed this article's citations yet. That second pass checks each claim against the source it cites.

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