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5-MeO-Pyr-T
5-MeO-Pyr-T is a tryptamine1 with an uncertain psychoactive classification; available reports tentatively place it among psychedelic research chemicals. The commentary describes its effects as outside familiar psychedelic terminology, with parenteral trials reporting rapid development of anesthesia1. Reported adverse outcomes include memory loss or blackouts after vaporized use and nausea during recovery from the anesthetic state1, with reports suggesting wide variation in its impact on different people1.
Dosage & Duration
Dosage
Doses are population estimates that vary widely between individuals.
Duration
Subjective Effects
Pharmacology
Pharmacodynamics
Available trial reports describe a rapid onset of anesthesia following parenteral administration.2
Pharmacokinetics
Interactions
An unlisted combination is an unknown one, not a safe one. Check a dedicated combination chart before mixing.
Tolerance
Harm Potential
Toxicity
Skin abnormalities lasting several days have been reported following use at doses as low as 3 mg smoked.
Nausea and vomiting appear to be common during the recovery period, occurring even at low doses of 3-4 mg smoked.
Psychosis Risk
Produces anesthesia-like unconsciousness with complete amnesia at doses as low as 3 mg smoked. Users have exhibited alarming behaviors including flailing, rolling, quivering, shaking, and wandering in public with no memory formation. One observer noted the user's actions were 'scary' to witness.
History & Culture
5-MeO-Pyr-T was documented in chemical literature alongside related pyrrolidine, piperidine, and morpholine analogues, including 5-MeO-mor-T and 5-MeO-pip-T.3 Reports of parenteral trials3 and speculation that related analogues, perhaps rather than this compound, might provide a useful clinical tool3 placed it within exploratory research on tryptamine analogues rather than an established psychedelic tradition.
Legality
Article Status
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